C5A Protein (AA 679-751)
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- Target See all C5A (C5a) Proteins
- C5A (C5a) (Complement Component 5a (C5a))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 679-751
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- AA 679-751
- Characteristics
- This protein carries no "tag". The protein has a calculated MW of 8.3 kDa. The protein migrates as 8.3 kDa under reducing (R) condition (SDS-PAGE).
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product C5a Protein
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Complement Component 5a (C5a) (AA 678-751) protein (His tag)
C5a Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Complement Component 5a (C5a) (AA 1-77) protein (His tag)C5a Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Complement Component 5a (C5a) (AA 679-755) (Active) protein (His tag)C5a Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 679-751) (Active) protein (Fc Tag)C5a Origin: Human Host: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Complement Component 5a (C5a) (AA 678-751) (Active) proteinC5a Origin: Cynomolgus Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE. Active
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- Target
- C5A (C5a) (Complement Component 5a (C5a))
- Alternative Name
- Complement Component C5a (C5a Products)
- Synonyms
- C5a Protein, C5b Protein, CPAMD4 Protein, Hc Protein, RGD1561905 Protein, complement C5 Protein, C5 Protein
- Background
- Human Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells, C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation, C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism, C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system, C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.
- Molecular Weight
- 8.3 kDa
- UniProt
- P01031
- Pathways
- Complement System, Carbohydrate Homeostasis
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