Thyroperoxidase Protein (full length)
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- Target See all Thyroperoxidase (TPO) Proteins
- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
- Protein Type
- Recombinant
- Protein Characteristics
- full length
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Origin
- Human
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Source
- Insect cells (Sf9)
- Application
- Western Blotting (WB), ELISA
- Characteristics
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Purified recombinant Human Thyroid Peroxidase protein
Expression System: Sf-9 insect cells - Purification
- Proprietary chromatographic technique
- Purity
- > 95 % pure
- Top Product
- Discover our top product TPO Protein
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Thyroid Peroxidase (TPO) (AA 19-846) protein (His tag)
TPO Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thyroid Peroxidase (TPO) (AA 32-834) protein (His tag)TPO Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Thyroid Peroxidase (TPO) (AA 672-779) protein (GST tag)TPO Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Thyroid Peroxidase (TPO) (AA 1-933) protein (GST tag)TPO Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- 16 mM HEPES, pH 7.6, with 166 mM NaCl, 0.06 mM Kl and 20 % glycerol.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- Target
- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
- Alternative Name
- Thyroid Peroxidase (TPO Products)
- Synonyms
- MSA Protein, TDH2A Protein, TPX Protein, TPO Protein, msa Protein, tpx Protein, xtpo Protein, LOC100218312 Protein, thyroid peroxidase Protein, TPO Protein, Tpo Protein, tpo Protein, LOC100547103 Protein
- Background
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Thyroid Peroxidase (TPO) represents one of the main autoantigenic targets in autoimmune thyroid disease of humans. Its identity with the formerly so-called `microsomal antigen` has been shown several years ago. As an integral membrane glycoprotein it is restricted to the apical plasma membrane of the follicular epithelial cells and comprises two identical subunits of approx. 100 kDa molecular weight. The hemoprotein TPO plays a key role in the thyroid hormone biosynthesis by catalysing both the iodination of tyrosyl residues and the coupling of iodotyrosyl residues in thyroglobulin (TG) to form precursors of the thyroid hormones T4 and T3.
Alternative Names: TPX protein, MSA protein, TPO protein - Molecular Weight
- 101 kDa
- Pathways
- Thyroid Hormone Synthesis
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