CCL5 Protein
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- Target See all CCL5 Proteins
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Sequence
- SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS
- Characteristics
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Purified recombinant Mouse RANTES protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract total human lymph °Cyte population and total Mouse T cell population using a concentration range of 1.0-10.0 ng/mL. - Purity
- > 98 % pure
- Endotoxin Level
- < 0.1 ng per μg (1 EU/μg) of RANTES.
- Top Product
- Discover our top product CCL5 Protein
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Comment
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Biological activity: Determined by its ability to chemoattract total human lymph DEG Cyte population and total Mouse T cell population using a concentration range of 1.0-10.0 ng/mL.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- Supplied lyophilized with no additives.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Target
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- Alternative Name
- RANTES (CCL5 Products)
- Synonyms
- Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein
- Background
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RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV).
Alternative Names: Regulation upon Activation Normal T cell Express Sequence protein, SIS-delta protein, CCL5 protein - Molecular Weight
- 7.8 kDa
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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