IL-3 beta Protein
IL-3 beta
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure
Active
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- Target See all IL-3 beta products
- IL-3 beta (Interleukin 3 beta (IL-3 beta))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Sequence
- MISDRGSDAH HLLRTLDCRT IALEILVKLP YPQVSGLNNS DDKANLRNST LRRVNLDEFL KSQEEFDSQD TTDIKSKLQK LKCCIPAAAS DSVLPGVYNK DLDDFKKKLR FYVIHLKDLQ PVSVSRPPQP TSSSDNFRPM TVEC
- Characteristics
-
Purified recombinant Human IL3 beta protein
Expression System: E.coli
Bioactivity: The ED50 was determined by the dose-dependent stimulation of the proliferation of thymidine uptake by Mouse MC-9 cells is 1.0 x 10^5 units/mg. - Purity
- > 98 % pure
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- < 0.1 ng per μg (1 EU/μg).
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Comment
-
Biological activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of thymidine uptake by Mouse MC-9 cells is 1.0 x 10^5 units/mg.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL. When dissolved, dilute further into aqueous buffered solutions.
- Buffer
- Sterile filtered through a 0.2 μm filter. Lyophilized from 5 mM Sodium Citrate pH 4.0.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- RT/-20 °C
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- Target
- IL-3 beta (Interleukin 3 beta (IL-3 beta))
- Alternative Name
- IL3 beta (IL-3 beta Products)
- Background
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IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines. IL3 is species-specific, variably glycosylated cytokine.
Alternative Names: Multi-CSF protein, IL 3, IL 3 protein, IL-3 protein, IL-3 beta protein, HCGF protein, Mast cell growth factor protein, IL-3, MCGF protein, Interleukin 3 beta protein, P-cell stimulation factor protein, IL3 - Molecular Weight
- 16.3 kDa
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