TRKA Protein (AA 34-407)
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- Target See all TRKA (NTRK1) Proteins
- TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 34-407
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Origin
- Human
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Source
- HEK-293T Cells
- Characteristics
- ED50 < 1 μg/mL, measured in a neutralization assay in the presence of 10 ng/mL human b-NGF using TF-1 Cells.
- Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product NTRK1 Protein
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Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (Active) protein (His tag)
NTRK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (Active) protein (Fc Tag)NTRK1 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (Active) protein (Fc Tag)NTRK1 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (Active) protein (His tag)NTRK1 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1) (AA 33-410) protein (Fc Tag)NTRK1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Human Tyrosine kinase receptor A remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Tyrosine kinase receptor A should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
- Alternative Name
- Tyrosine Kinase Receptor A (NTRK1 Products)
- Synonyms
- MTC Protein, TRK Protein, TRK1 Protein, TRKA Protein, Trk-A Protein, p140-TrkA Protein, CDHF12 Protein, CDHR16 Protein, HSCR1 Protein, MEN2A Protein, MEN2B Protein, MTC1 Protein, PTC Protein, RET-ELE1 Protein, RET51 Protein, Trk Protein, C80751 Protein, Tkr Protein, TrkA Protein, trk Protein, trka Protein, CTRKA Protein, trkA Protein, neurotrophic receptor tyrosine kinase 1 Protein, ret proto-oncogene Protein, neurotrophic tyrosine kinase, receptor, type 1 Protein, NTRK1 Protein, RET Protein, Ntrk1 Protein, ntrk1 Protein
- Background
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Tyrosine kinase receptor A (Trk-A) is a member of the neurotrophic tyrosine kinase receptor family which includes three members: Trk-A, Trk-B and Trk-C. Trk-A is involved in the development and maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic neurons.
Synonyms: Trk-A, NTRK1, MTC, TRK, TRKA - Molecular Weight
- 65-85 kDa, observed by reducing SDS-PAGE.
- Pathways
- RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process
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