KIT Ligand Protein (KITLG) (AA 26-189)
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- Target See all KIT Ligand (KITLG) Proteins
- KIT Ligand (KITLG)
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 26-189
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Origin
- Rat
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Source
- Yeast (Pichia pastoris)
- Characteristics
- ED50 < 25 ng/mL, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 4x 10^4 units/mg.
- Purity
- > 95 % by SDS-PAGE analysis.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product KITLG Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant rat Stem Cell Factor (rrSCF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rrSCF should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- KIT Ligand (KITLG)
- Alternative Name
- Stem Cell Factor (SCF) (KITLG Products)
- Background
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Stem Cell Factor (SCF) is a hematopoietic growth factor that binds to the c-Kit receptor. SCF exerts its activity during the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors. Recombinant rat Stem Cell Factor (rrSCF) produced in P. pastoris is a single glycosylated polypeptide chain containing 164 amino acids. A fully biologically active molecule, rrSCF has a molecular mass of 18.3 kDa analyzed by reducing SDS-PAGE.
Synonyms: Stem Cell Factor, c-Kit Ligand, Mast Cell Growth Factor (MGF), Steel Factor - Molecular Weight
- 18.3 kDa, observed by reducing SDS-PAGE.
- UniProt
- P21581
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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