PF4 Protein (AA 32-101)
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- Target See all PF4 Proteins
- PF4 (Platelet Factor 4 (PF4))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 32-101
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Origin
- Human
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Source
- HEK-293T Cells
- Characteristics
- ED50 < 10 μg/mL, measured by its ability to inhibit human FGF-basic-dependent proliferation of NR6R 3T3 mouse fibroblast cells.
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product PF4 Protein
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Platelet Factor 4 (PF4) (AA 30-105) protein (Fc Tag)
PF4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag)PF4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 32-101) protein (His-Avi Tag,Biotin)PF4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Platelet Factor 4 (PF4) (AA 32-101) protein (Fc Tag)PF4 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Platelet Factor 4 (PF4) (AA 1-101) protein (GST tag)PF4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Factor 4 (PF4) (AA 34-101) protein (Fc Tag)PF4 Origin: Cynomolgus Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Platelet Factor 4 (PF4) (AA 32-101) protein (His tag)PF4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant human platelet factor 4 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human platelet factor 4 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- PF4 (Platelet Factor 4 (PF4))
- Alternative Name
- Platelet Factor 4/CXCL4 (PF4 Products)
- Background
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Platelet factor 4, also known as CXCL4, is expressed in megakaryocytes and stored in the alpha-granules of platelets. Recombinant human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Platelet factor 4 can be antiproliferative and antiangiogenic, at least in part via interfering with FGF2 and VEGF heparin binding and thus inhibiting their signaling. However, it can also be proinflammatory and proatherogenic through multiple effects on monocytes, macrophages and endothelial cells.
Synonyms: PF-4, CXCL4, SCYB4,Platelet Factor-4, CXCL4, Oncostatin A, Ironplact - Molecular Weight
- -7.8 kDa, observed by non-reducing SDS-PAGE.
- UniProt
- P02776
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