PDGFD Protein (AA 250-370)
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- Target See all PDGFD Proteins
- PDGFD (Platelet Derived Growth Factor D (PDGFD))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 250-370
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Origin
- Human
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Source
- CHO Cells
- Characteristics
- ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
- Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product PDGFD Protein
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Platelet Derived Growth Factor D (PDGFD) (AA 19-370) protein (His tag)
PDGFD Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Platelet Derived Growth Factor D (PDGFD) (AA 1-364) protein (GST tag)PDGFD Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor D (PDGFD) (AA 24-370) protein (His tag)PDGFD Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Platelet Derived Growth Factor D (PDGFD) (AA 24-123) protein (GST tag)PDGFD Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor D (PDGFD) (AA 19-370) protein (His tag)PDGFD Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Platelet Derived Growth Factor D (PDGFD) (AA 250-370) protein (Fc Tag)PDGFD Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- PDGFD (Platelet Derived Growth Factor D (PDGFD))
- Abstract
- PDGFD Products
- Synonyms
- IEGF Protein, SCDGF-B Protein, SCDGFB Protein, Scdgfb Protein, rSCDGF-B Protein, PDGFD Protein, 1110003I09Rik Protein, platelet derived growth factor D Protein, platelet-derived growth factor, D polypeptide Protein, PDGFD Protein, Pdgfd Protein
- Background
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PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Synonyms: platelet-derived growth factor D, IEGF, SCDGFB - Molecular Weight
- 19-21 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q9GZP0
- Pathways
- RTK Signaling, Platelet-derived growth Factor Receptor Signaling
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