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NGFR Protein (AA 29-250)

NGFR Origin: Human Host: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2018287
  • Target See all NGFR Proteins
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 29-250
    Origin
    • 4
    • 3
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293T Cells
    Characteristics
    ED50 < 0.4 μg /mL, measured in a neutrolization assay using TF-1 cells in the presence of 10 ng/mL human b-NGF.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant human NGF Receptor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Alternative Name
    NGF Receptor (NGFR Products)
    Background
    NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
    Synonyms: Gp80-LNGFR, p75 ICD, CD271, TNFRSF16
    Molecular Weight
    32-60 kDa, observed by reducing SDS-PAGE.
    UniProt
    P08138
    Pathways
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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