NGFR Protein (AA 29-250)
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- Target See all NGFR Proteins
- NGFR (Nerve Growth Factor Receptor (NGFR))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 29-250
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Origin
- Human
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Source
- HEK-293T Cells
- Characteristics
- ED50 < 0.4 μg /mL, measured in a neutrolization assay using TF-1 cells in the presence of 10 ng/mL human b-NGF.
- Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product NGFR Protein
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Nerve Growth Factor Receptor (NGFR) (AA 1-427) protein (GST tag)
NGFR Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nerve Growth Factor Receptor (NGFR) (AA 32-140) protein (GST tag)NGFR Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Nerve Growth Factor Receptor (NGFR) (Active) protein (Fc Tag)NGFR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Nerve Growth Factor Receptor (NGFR) protein (His tag)NGFR Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
Nerve Growth Factor Receptor (NGFR) protein (Myc-DYKDDDDK Tag)NGFR Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant human NGF Receptor remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human NGF Receptor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- NGFR (Nerve Growth Factor Receptor (NGFR))
- Alternative Name
- NGF Receptor (NGFR Products)
- Synonyms
- ngfr Protein, wu:fb38c02 Protein, wu:fc10h01 Protein, CD271 Protein, Gp80-LNGFR Protein, TNFRSF16 Protein, p75(NTR) Protein, p75NTR Protein, LNGFR Protein, RNNGFRR Protein, Tnfrsf16 Protein, p75 Protein, NRH1b Protein, fullback Protein, nrh1 Protein, p75ntr Protein, tnfrsf16 Protein, p75NGFR Protein, nerve growth factor receptor Protein, neurotrophin receptor associated death domain Protein, nerve growth factor receptor S homeolog Protein, nerve growth factor receptor (TNFR superfamily, member 16) Protein, NGFR Protein, nradd Protein, Ngfr Protein, ngfr.S Protein
- Background
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NGF Receptor, also known as Gp80-LNGFR, p75 ICD, CD271 and TNFRSF16, is a type I transmembrane protein belonging to the TNF receptor family. It is expressed by both neuronal and non-neuronal cells. Signaling through NGF Receptor has been shown to regulate gene expression, cell migration and death. A truncated NGF Receptor containing only the extracellular domain has been detected in plasma, amniotic fluid and urine, and acts as a potent NGF antagonist.
Synonyms: Gp80-LNGFR, p75 ICD, CD271, TNFRSF16 - Molecular Weight
- 32-60 kDa, observed by reducing SDS-PAGE.
- UniProt
- P08138
- Pathways
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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