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M-CSF/CSF1 Protein (AA 33-187)

CSF1 Origin: Mouse Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC. Active
Catalog No. ABIN2018209
  • Target See all M-CSF/CSF1 (CSF1) Proteins
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 33-187
    Origin
    • 27
    • 14
    • 6
    • 1
    Mouse
    Source
    • 19
    • 15
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    CHO Cells
    Characteristics
    ED50< 3 ng/mL, measured in a cell proliferation assay using Murine M-NFS-60 cells, corresponding to a specific activity of > 3.3×10^5 units/mg.
    Purity
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product CSF1 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant murine Macrophage-Colony Stimulating Factor (M-CSF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmM-CSF should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    Alternative Name
    Macrophage Colony Stimulating Factor (M-CSF) (CSF1 Products)
    Synonyms
    CSF-1 Protein, MCSF Protein, C87615 Protein, Csfm Protein, op Protein, csf1-1 Protein, zgc:172186 Protein, CSF1 Protein, csf1-2 Protein, zgc:158436 Protein, colony stimulating factor 1 Protein, colony stimulating factor 1 (macrophage) Protein, colony stimulating factor 1a (macrophage) Protein, macrophage colony-stimulating factor 1 Protein, macrophage colony stimulating factor Protein, colony stimulating factor 1b (macrophage) Protein, CSF1 Protein, Csf1 Protein, csf1a Protein, LOC396599 Protein, LOC100860895 Protein, csf1b Protein
    Background
    Macrophage-Colony Stimulating Factor (M-CSF), also known as Colony Stimulating Factor-1 (CSF-1), can stimulate the survival, proliferation and differentiation of mononuclear phagocytes, in addition to the spreading and motility of macrophages[1]. M-CSF is mainly produced by monocytes, macrophages, fibroblasts, and endothelial cells[2]. M-CSF interaction with its receptor, c-fms, has been implicated in the growth, invasion, and metastasis of of several diseases, including breast and endometrial cancers [1][3][4] .
    Synonyms: CSF1, CSF-1, MCSF
    Molecular Weight
    35-44 kDa, observed by non-reducing SDS-PAGE.
    UniProt
    Q3U4F9
    Pathways
    RTK Signaling
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