FGF7 Protein (AA 32-194)
-
- Target See all FGF7 Proteins
- FGF7 (Fibroblast Growth Factor 7 (FGF7))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 32-194
-
Origin
- Human
-
Source
- CHO Cells
- Characteristics
- ED50 < 1 ng /mL, measured in a proliferation assay using 4MBr5 cells.
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product FGF7 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
-
- Target
- FGF7 (Fibroblast Growth Factor 7 (FGF7))
- Alternative Name
- Keratinocyte Growth Factor (KGF) (FGF7 Products)
- Synonyms
- HBGF-7 Protein, KGF Protein, Kgf Protein, kgf Protein, FGF-7 Protein, fgf7 Protein, fibroblast growth factor 7 Protein, fibroblast growth factor 7 L homeolog Protein, FGF7 Protein, Fgf7 Protein, fgf7 Protein, fgf7.L Protein
- Background
-
Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7 - Molecular Weight
- 16-18 kDa, observed by reducing SDS-PAGE.
- UniProt
- P21781
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
-