IFNB1 Protein (AA 22-187)
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- Target See all IFNB1 Proteins
- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 22-187
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Origin
- Human
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Source
- HEK-293T Cells
- Characteristics
- ED50 < 0.1 ng/mL, measured in a proliferation assay using TF-1 Cells.
- Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IFNB1 Protein
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Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)
IFNB1 Origin: Mouse Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-187) protein (Fc Tag)IFNB1 Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-182) protein (His tag)IFNB1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Interferon, beta 1, Fibroblast (IFNB1) (AA 102-187) protein (GST tag)IFNB1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon, beta 1, Fibroblast (IFNB1) (AA 1-187) protein (GST tag)IFNB1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Interferon, beta 1, Fibroblast (IFNB1) (AA 22-187), (full length) protein (GST tag)IFNB1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Human Interferon-beta remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interferon-beta should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
- Alternative Name
- Interferon-beta (IFNB1 Products)
- Synonyms
- IFB Protein, IFF Protein, IFNB Protein, IFN-beta Protein, Ifb Protein, Ifnb Protein, IFNb Protein, interferon beta 1 Protein, interferon beta 1, fibroblast Protein, interferon, beta 1, fibroblast Protein, IFNB1 Protein, Ifnb1 Protein
- Background
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Interferon-beta (IFN-beta), acting via STAT1 and STAT2, is known to upregulate and downregulate a wide variety of genes, most of which are involved in the antiviral immune response. It is a member of Type I IFNs, which include IFN-alpha, -beta, tau, and omega. IFN-beta plays an important role in inducing non-specific resistance against a broad range of viral infections. It also affects cell proliferation and modulates immune responses.
Synonyms: Leukocyte interferon, B cell interferon, Type I interferon - Molecular Weight
- 23 kDa, observed by reducing SDS-PAGE.
- UniProt
- P01574
- Pathways
- JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
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