CCL16 Protein (AA 24-120)
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- Target See all CCL16 Proteins
- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 24-120
- Origin
- Human
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Source
- CHO Cells
- Characteristics
- The EC50 value of human HCC-4/CCL16 on Ca2+ mobilization assay in CHO-K1/Ga15/hCCR1 cells (human Ga15 and human CCR1 stably expressed in CHO-K1 cells) is less than 1.5 μg/mL.
- Purity
- > 98 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product CCL16 Protein
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Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)
CCL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 25-120) protein (GST tag)CCL16 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His tag)CCL16 Origin: Human Host: Yeast (Pichia pastoris) Recombinant > 95 % WB, SDS, ELISA, IP
Chemokine (C-C Motif) Ligand 16 (CCL16) (AA 24-120) protein (His-SUMO Tag)CCL16 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant human HCC4/CCL16 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human HCC4/CCL16 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))
- Alternative Name
- HCC-4/CCL16 (CCL16 Products)
- Synonyms
- CKb12 Protein, HCC-4 Protein, ILINCK Protein, LCC-1 Protein, LEC Protein, LMC Protein, Mtn-1 Protein, NCC-4 Protein, NCC4 Protein, SCYA16 Protein, SCYL4 Protein, C-C motif chemokine ligand 16 Protein, CCL16 Protein, Ccl16 Protein
- Background
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Human HCC4, also named NCC4and Chemokine (C-C motif) ligand 16 (CCL16) is a small cytokine belonging to the CC chemokine family that is known under several pseudonyms, including Liver-expressed chemokine (LEC) and Monotactin-1 (MTN-1). It can signal through the CCR8 and CCR1 receptors, and it is chemotactic towards monocytes and lymphocytes but not neutrophils. HCC-4 is expressed weakly by some lymphocytes, including NK cells, T cells, and some T cell clones. The expression of HCC-4 in monocytes is greatly up-regulated in the presence of IL-10. HCC-4 induces a calcium flux in thp-1 cells that are desensitized prior to the expression of RANTES.
Synonyms: HCC-4/CCL16, Human - Molecular Weight
- 12 kDa, observed by reducing SDS-PAGE.
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