Growth Hormone 1 Protein (GH1)
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- Target See all Growth Hormone 1 (GH1) Proteins
- Growth Hormone 1 (GH1)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- CHO Cells
- Characteristics
- ED50 < 0.5 ng/mL, measured in a cell proliferation assay using Nb2-11 cells, corresponding to a specific activity of >2 x 10^6 units/mg
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product GH1 Protein
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Growth Hormone 1 (GH1) (Active) protein
GH1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Growth Hormone 1 (GH1) (AA 1-217) protein (GST tag)GH1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Hormone 1 (GH1) proteinGH1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Human Growth Hormone (GH) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhGH should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- Growth Hormone 1 (GH1)
- Alternative Name
- Growth Hormone (GH1 Products)
- Background
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Growth hormone (GH), also known as somatotropin, is a member of a family of growth factors that includes prolactin, placental lactogens, proliferins, and somatolactin. It is synthesized primarily by somatotropes in the anterior pituitary and is stored in secretary granules. The pulsatile release of GH into circulation is regulated by the concerted actions of the hypothalamic hormones-GH-releasing hormone (GHRH) and somatostatin (SST) - as well as by signals from the periphery - ghrelin and leptin. The human GH cDNA encodes a 217 amino acid (aa) residue precursor protein with a 26 aa putative signal peptide. By alternative splicing, at least four isoforms of GH have been identified.
Synonyms: GH1, GH, GHN, GH-N, hGH-N,Pituitary growth hormone, Growth hormone 1, Somatotropin - Molecular Weight
- 20-24 kDa, observed by non-reducing SDS-PAGE.
- Pathways
- NF-kappaB Signaling, JAK-STAT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Response to Growth Hormone Stimulus, Regulation of Hormone Biosynthetic Process
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