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FGF18 Protein (AA 27-199)

FGF18 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN2017815
  • Target See all FGF18 Proteins
    FGF18 (Fibroblast Growth Factor 18 (FGF18))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 27-199
    Origin
    • 7
    • 4
    • 3
    • 1
    Human
    Source
    • 11
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Characteristics
    ED50 < 10 ng/mL, measured by a cell proliferation assay using 3T3 Cells, corresponding to a specific activity of > 1.0x 105 units/mg.
    AA 27 -199, expressed with an N-terminal Met.
    Purity
    > 95 % by SDS-PAGE and HPLC analyses.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product FGF18 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant human Fibroblast Growth Factor-18 (rhFGF-18) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhFGF-18 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
    Expiry Date
    6 months
  • Target
    FGF18 (Fibroblast Growth Factor 18 (FGF18))
    Alternative Name
    Fibroblast Growth Factor-18 (FGF-18) (FGF18 Products)
    Synonyms
    FGF-18 Protein, ZFGF5 Protein, D130055P09Rik Protein, fgf18 Protein, FGF18 Protein, fgf18l Protein, fibroblast growth factor 18 Protein, fibroblast growth factor 18a Protein, fibroblast growth factor 18b Protein, FGF18 Protein, Fgf18 Protein, fgf18a Protein, Tsp_09844 Protein, fgf18b Protein
    Background
    Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.Recombinant human Fibroblast Growth Factor-18 (rhFGF-18) produced in E. coli is a single non-glycosylated polypeptide chain containing 174 amino acids. A fully biologically active molecule, rhFGF-18 has a molecular mass of 20.3 kDa analyzed by reducing SDS-PAGE.
    Synonyms: Fibroblast Growth Factor-18, zFGF5, FGFI
    Molecular Weight
    20.3 kDa, observed by reducing SDS-PAGE.
    UniProt
    O76093
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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