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FGF16 Protein (AA 2-207)

FGF16 Origin: Human Host: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE and HPLC.
Catalog No. ABIN2017808
  • Target See all FGF16 Proteins
    FGF16 (Fibroblast Growth Factor 16 (FGF16))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 2-207
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    CHO Cells
    Characteristics
    Measured in a cell proliferation assay using 3T3 mouse fibroblast cell, The ED50 for this effect is < 20 ng/mL.
    Purity
    > 95 % as analyzed by SDS-PAGE and HPLC.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product FGF16 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant Human Fibroblast Growth Factor-16 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Fibroblast Growth Factor-16 should be stable up to 1 week at 4 °C or up to 3 months at -20 °C.
    Expiry Date
    6 months
  • Target
    FGF16 (Fibroblast Growth Factor 16 (FGF16))
    Alternative Name
    Fibroblast Growth Factor-16 (FGF-16) (FGF16 Products)
    Synonyms
    FGF16 Protein, FGF-16 Protein, fibroblast growth factor 16 Protein, FGF16 Protein, fgf16 Protein, Fgf16 Protein
    Background
    Fibroblast Growth Factor-16 (FGF-16) is a heparin binding growth factor, a member of the FGF family. All FGF family members are heparin binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The rat homolog is predominantly expressed in embryonic brown adipose tissue and has significant mitogenic activity, which suggests a role in proliferation of embryonic brown adipose tissue. FGF-16 is most similar to FGF-9 (73 % amino acid identity). The protein sequence of human FGF-16 displays 98.6 % identity with rat FGF-16. Chimpanzee FGF-16 (207 amino acids), chicken FGF-16 (207 amino acids), and zebrafish FGF-16 (203 amino acids) show 100 %, 89.9 %, and 79.2 % total amino acid identity with human FGF-16.Recombinant human FGF-16 produced in CHO cells is a polypeptide chain containing 206 amino acids. A fully biologically active molecule, rhFGF-16 has a molecular mass of 23 kDa analyzed by reducing SDS-PAGE.
    Synonyms: FGF-16, Fibroblast Growth Factor-16, FGFG
    Molecular Weight
    23 kDa, observed by reducing SDS-PAGE.
    UniProt
    O43320
    Pathways
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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