FGF10 Protein (AA 62-209)
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- Target See all FGF10 Proteins
- FGF10 (Fibroblast Growth Factor 10 (FGF10))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 62-209
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Characteristics
- ED50 < 10 ng/mL, measured by a cell proliferation assay using 4MBr-5 cells, corresponding to a specific activity of > 1.0x 10^5 units/mg.
- Purity
- > 95 % as analyzed by SDS-PAGE and HPLC.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product FGF10 Protein
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Fibroblast Growth Factor 10 (FGF10) (AA 38-208) protein (Biotin)
FGF10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Fibroblast Growth Factor 10 (FGF10) proteinFGF10 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90% as determined by Tris-Bis PAGE
Fibroblast Growth Factor 10 (FGF10) (AA 37-215) protein (His tag)FGF10 Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Fibroblast Growth Factor 10 (FGF10) (AA 1-208) protein (GST tag)FGF10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Fibroblast Growth Factor 10 (FGF10) (AA 38-137) protein (GST tag)FGF10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmFGF-10 remains stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- Expiry Date
- 6 months
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- Target
- FGF10 (Fibroblast Growth Factor 10 (FGF10))
- Alternative Name
- Fibroblast Growth Factor-10 (FGF-10) (FGF10 Products)
- Synonyms
- fgf10 Protein, fgf-10 Protein, wu:fd11d03 Protein, zgc:109774 Protein, FGF10 Protein, AEY17 Protein, BB213776 Protein, Fgf-10 Protein, Gsfaey17 Protein, FGF-10 Protein, fibroblast growth factor 10a Protein, fibroblast growth factor 10 Protein, fgf10a Protein, FGF10 Protein, fgf10 Protein, Fgf10 Protein
- Background
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Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF, and both KGF and FGF-10 activate the receptor FGFR2-IIIb. However, unlike KGF, which induces the proliferation and differentiation of various epithelial cells, FGF-10 is an essential factor for the budding and branching morphogenesis during multi-organ development via mesenchymal-epithelial interactions. FGF-10 is crucial for lung and limb development and is regulated by Shh during early development. Recombinant mouse Fibroblast Growth Factor-10 (rmFGF-10) produced in E. coli is a single non-glycosylated polypeptide chain containing 148 amino acids. A fully biologically active molecule, rmFGF-10 has a molecular mass of 17.0 kDa analyzed by reducing SDS-PAGE.
Synonyms: Fibroblast Growth Factor-10, FGFA, Keratinocyte growth factor-2 - Molecular Weight
- 17.0 kDa, observed by reducing SDS-PAGE.
- UniProt
- O35565
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus
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