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CXCL3 Protein (AA 28-100)

CXCL3 Origin: Mouse Host: CHO Cells Recombinant > 98 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2017730
  • Target See all CXCL3 Proteins
    CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 28-100
    Origin
    • 6
    • 3
    • 3
    • 1
    Mouse
    Source
    • 12
    • 1
    • 1
    CHO Cells
    Characteristics
    The EC50 value of mouse DCIP-1/CXCL3 on Ca2+ mobilization assay in CHO-K1/Ga15/mCXCR2 cells (human Ga15 and mouse CXCR2 stably expressed in CHO-K1 cells) is less than 100 ng/mL.
    Purity
    > 98 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product CXCL3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant Mouse DCIP-1/CXCL3 remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Mouse DCIP-1/CXCL3 should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    CXCL3 (Chemokine (C-X-C Motif) Ligand 3 (CXCL3))
    Alternative Name
    DCIP-1/CXCL3 (CXCL3 Products)
    Synonyms
    CXCL3 Protein, CINC-2b Protein, GRO3 Protein, GROg Protein, MIP-2b Protein, MIP2B Protein, SCYB3 Protein, Cinc-2 Protein, Cinc2 Protein, Gm1960 Protein, Dcip1 Protein, C-X-C motif chemokine ligand 3 Protein, chemokine (C-X-C motif) ligand 3 Protein, CXCL3 Protein, Cxcl3 Protein
    Background
    Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family that is also known as DCIP-1 (dendritic cell inflammatory protein-1) or MIP 2b. CXCL3 controls migration and adhesion of monocytes and mediates its effect on its target cell by interacting with cell surface chemokine receptor CXCR2. It has been shown that CXCL3 regulates the migration of precursors of cerebellar granule neurons toward the internal layers of cerebellum, during morphogenesis. Recombinant mouse DCIP-1/CXCL3 produced in CHO cells is a polypeptide chain containing 73 amino acids. A fully biologically active molecule, rmDCIP-1/CXCL3 has a molecular mass of 8 kDa analyzed by reducing SDS-PAGE.
    Synonyms: DCIP-1/CXCL3, Mouse
    Molecular Weight
    8 kDa, observed by reducing SDS-PAGE.
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Autophagy
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