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Betacellulin Protein (BTC) (AA 32-111)

BTC Origin: Human Host: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2017687
  • Target See all Betacellulin (BTC) Proteins
    Betacellulin (BTC)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 32-111
    Origin
    • 11
    • 4
    • 4
    • 2
    • 2
    Human
    Source
    • 13
    • 4
    • 3
    • 1
    • 1
    HEK-293T Cells
    Characteristics
    ED50 < 4 pg/mL, measured in a cell proliferation assay using 3T3 cells.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
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    Discover our top product BTC Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant Human Betacellulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Betacellulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    Betacellulin (BTC)
    Alternative Name
    Betacellulin (BTC Products)
    Background
    Betacellulin (BTC) is a member of the EGF family of cytokines that also includes EGF, TGF-alpha, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin, Heregulin and Neuregulins. At the amino acid sequence level, human mature BTC protein exhibits 80 % identity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum.
    Synonyms: BTC
    Molecular Weight
    15-18 kDa, observed by reducing SDS-PAGE.
    UniProt
    P35070
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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