IL21 Receptor Protein (AA 20-236) (His tag)
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- Target See all IL21 Receptor (IL21R) Proteins
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 20-236
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This IL21 Receptor protein is labelled with His tag.
- Purpose
- Recombinant Human IL-21 Receptor/IL-21R (C-6His)
- Sequence
- CPDLVCYTDY LQTVICILEM WNLHPSTLTL TWQDQYEELK DEATSCSLHR SAHNATHATY TCHMDVFHFM ADDIFSVNIT DQSGNYSQEC GSFLLAESIK PAPPFNVTVT FSGQYNISWR SDYEDPAFYM LKGKLQYELQ YRNRGDPWAV SPRRKLISVD SRSVSLLPLE FRKDSSYELQ VRAGPMPGSS YQGTWSEWSD PVIFQTQSEE LKEGWNPVDH HHHHH
- Characteristics
- Recombinant Human Interleukin-21 receptor/IL-21R is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Cys20-Pro236) of Human IL-21R fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product IL21R Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- Alternative Name
- Interleukin-21 Receptor/IL-21R (IL21R Products)
- Synonyms
- IL21R Protein, il-21ra.a Protein, CD360 Protein, NILR Protein, interleukin 21 receptor Protein, interleukin 21 receptor, tandem duplicate 1 Protein, IL21R Protein, il21r.1 Protein, Il21r Protein
- Sub Type
- Fusionprotein
- Background
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Interleukin-21 receptor is also known as IL-21 receptor, IL-21R, CD360. In humans, it is encoded by the IL21R gene. It belongs to the type I cytokine receptor family. Type 4 subfamily contains 2 fibronectin type-III domains. Interleukin-21 receptor is selectively expressed in lymphoid tissues and highly expressed in thymus and spleen. IL-21 is produced by CD4+ T cells in response to antigenic stimulation. Its action enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated B-cells into plasma cells and memory B-cells. It also promotes the anti-tumor activity of CD8+ T-cells and NK cells.
Alternative Names: Interleukin-21 receptor is also known as IL-21 receptor, IL-21R, CD360. - Molecular Weight
- 26 kDa
- UniProt
- Q9HBE5
- Pathways
- JAK-STAT Signaling
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