NFYA Protein (AA 1-318)

Catalog No. ABIN1880589

Product Details

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Protein Type: Recombinant

Protein Characteristics: AA 1-318

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Nuclear Transcription Factor Y Subunit α/NFYA

Sequence: MEQYTANSNS STEQIVVQAG QIQQQVQGQP LMVQVSGGQL ITSTGQPIMV QAVPGGQGQT IMQVPVSGTQ GLQQIQLVPP GQIQIQGGQA VQVQGQQGQT QQIIIQQPQT AVTAGQTQTQ QQIAVQGQQV AQTAEGQTIV YQPVNADGTI LQQVTVPVSG MITIPAASLA GAQIVQTGAN TNTTSSGQGT VTVTLPVAGN VVNSGGMVMM VPGAGSVPAI QRIPLPGAEM LEEEPLYVNA KQYNRILKRR QARAKLEAEG KIPKERRKYL HESRHRHAMA RKRGEGGRFF SPKEKDSPHM QDPNQADEEA MTQIIRVS

Characteristics: Recombinant Human Nuclear Transcription Factor Y Subunit α/NFYA is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser318) of Human NFYA.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Alternative Name: Nuclear Transcription Factor Y Subunit alpha/nfya (NFYA Products)

Synonyms: wu:fb16e03 Protein, ik:tdsubc_2b6 Protein, xx:tdsubc_2b6 Protein, NFYA Protein, CBF-A Protein, CBF-B Protein, HAP2 Protein, NF-YA Protein, AA407810 Protein, Cbf-b Protein, SEZ-10 Protein, SEZ10 Protein, nuclear transcription factor Y, alpha Protein, nuclear transcription factor Y subunit alpha Protein, nuclear transcription factor-Y alpha Protein, nfya Protein, NFYA Protein, Nfya Protein

Background: Nuclear Transcription Factor Y Subunit α (NFYA) is a member of the NFYA/HAP2 subunit family. NFYA founctions as a heterotrimeric transcription factor , which is composed of three components, NF-YA, NF-YB and NF-YC, binds to CCAAT motifs in the promoter regions in a variety of genes. NFYA forms a highly conserved transcription factor which stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.

Molecular Weight: 33.9 kDa

Pathways: Regulation of Lipid Metabolism by PPARalpha