UBE2D3 Protein (AA 1-147)

Catalog No. ABIN1880587

Product Details

Target: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Protein Type: Recombinant

Protein Characteristics: AA 1-147

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Ubiquitin-Conjugating Enzyme E2 D3/UBE2D3

Sequence: MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF FLTIHFPTDY PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV PELARIYKTD RDKYNRISRE WTQKYAM

Characteristics: Recombinant Human Ubiquitin-conjugating enzyme E2 D3/UBE2D3 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Met147) of Human UBE2D3.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT,10 % glycerol, pH 7.5.

Preservative: Dithiothreitol (DTT)

Precaution of Use: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))

Alternative Name: Ubiquitin-Conjugating Enzyme E2 D3/UBE2D3 (UBE2D3 Products)

Synonyms: E2(17)KB3 Protein, UBC4/5 Protein, UBCH5C Protein, eff Protein, fb36f02 Protein, wu:fb36f02 Protein, zgc:56340 Protein, 1100001F19Rik Protein, 9430029A22Rik Protein, AA414951 Protein, UBE2D3P Protein, Xubc4 Protein, e2(17)kb3 Protein, ubc4/5 Protein, ubch5c Protein, ube2d3.1 Protein, ube2d2 Protein, xubc4 Protein, wu:fj13d01 Protein, zgc:73200 Protein, ubiquitin conjugating enzyme E2 D3 Protein, ubiquitin-conjugating enzyme E2D 3 Protein, ubiquitin conjugating enzyme E2 D3 L homeolog Protein, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like Protein, UBE2D3 Protein, ube2d3 Protein, Ube2d3 Protein, LOC100223566 Protein, ube2d3.L Protein, ube2d2l Protein

Background: UBE2D3 is an enzyme that belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.

Molecular Weight: 16.6 kDa

UniProt: P61077

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades