NGFB Protein

Catalog No. ABIN1880418

Product Details

Target: NGFB (Nerve Growth Factor beta (NGFB))

Protein Type: Native

Biological Activity: Active

Origin: Mouse

Source: Mouse

Purity: > 95 % by SDS-PAGE

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with sterile 18 mΩ/cm^3 H2O.

Buffer: 10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)

Preservative: Without preservative

Storage: 4 °C

Target Details

Target: NGFB (Nerve Growth Factor beta (NGFB))

Alternative Name: NGF beta (NGFB Products)

Synonyms: NGFB Protein, ngfb Protein, ns:zft386 Protein, xx:zft386 Protein, zgc:109730 Protein, hsan5 Protein, beta-ngf Protein, Ngfb Protein, Beta-NGF Protein, HSAN5 Protein, beta-NGF Protein, nerve growth factor Protein, nerve growth factor b (beta polypeptide) Protein, beta-Nerve growth factor Protein, nerve growth factor (beta polypeptide) Protein, NGF Protein, ngfb Protein, FPV072 Protein, FPV076 Protein, ngf Protein, Ngf Protein

Background: Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.

Molecular Weight: 26.5 kDa

Pathways: NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size