HIST4H4 Protein
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- Target See all HIST4H4 products
- HIST4H4 (Histone Cluster 4, H4 (HIST4H4))
- Protein Type
- Native
- Origin
- Pig
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Source
- Pig
- Application
- ELISA, Western Blotting (WB), Immunoprecipitation (IP), SDS-PAGE (SDS)
- Purity
- > 90 %
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- Application Notes
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Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Optimal working dilutions must be determined by end user. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute in sterile PBS, pH 7.2 - pH 7.4.
- Buffer
- Supplied as lyophilized form in 50 mM TRIS, 200 mM NaCl
- Handling Advice
- Avoid repeated freeze/thaw cycles
- Storage
- 4 °C
- Storage Comment
- Store at 2-8 °C for one month. Aliquot and store at -80 °C for 12 months.
- Expiry Date
- 12 months
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- Target
- HIST4H4 (Histone Cluster 4, H4 (HIST4H4))
- Abstract
- HIST4H4 Products
- Synonyms
- H4/p Protein, histone cluster 4 H4 Protein, HIST4H4 Protein
- Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element.
- Pathways
- Telomere Maintenance
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