STX8 Protein (AA 1-215)

Catalog No. ABIN1692453

Product Details

Target: STX8 (Syntaxin 8 (STX8))

Protein Type: Recombinant

Protein Characteristics: AA 1-215

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Syntaxin-8/STX8

Sequence: MAPDPWFSTY DSTCQIAQEI AEKIQQRNQY ERKGEKAPKL TVTIRALLQN LKEKIALLKD LLLRAVSTHQ ITQLEGDRRQ NLLDDLVTRE RLLLASFKNE GAEPDLIRSS LMSEEAKRGA PNPWLFEEPE ETRGLGFDEI RQQQQKIIQE QDAGLDALSS IISRQKQMGQ EIGNELDEQN EIIDDLANLV ENTDEKLRNE TRRVNMVDRK SASCG

Characteristics: Recombinant Human Syntaxin-8/STX8 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Gly215) of Human STX8.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 5 months

Target Details

Target: STX8 (Syntaxin 8 (STX8))

Alternative Name: STX8 (STX8 Products)

Synonyms: CG4109 Protein, Dm Syx8 Protein, DmSyx8 Protein, Dmel\\CG4109 Protein, SYX8 Protein, Syx Protein, zgc:64079 Protein, syntaxin-8 Protein, STX8 Protein, GB11192 Protein, MGC116467 Protein, DDBDRAFT_0217663 Protein, DDBDRAFT_0231533 Protein, DDB_0217663 Protein, DDB_0231533 Protein, CARB Protein, 0610007H08Rik Protein, 1110002H11Rik Protein, 4930571E13Rik Protein, Syntaxin 8 Protein, syntaxin 8 Protein, syntaxin-8 Protein, syntaxin 8 S homeolog Protein, Syx8 Protein, stx8 Protein, STX8 Protein, LOC552098 Protein, stx8.S Protein, syn8A Protein, Stx8 Protein

Background: Syntaxin-8 is a single-pass type IV membrane protein which belongs to the syntaxin family. It contains one t-SNARE coil homology domain. STX8 is highly expressed in heart, also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. STX8 is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. It as a vesicle trafficking protein functions in the early secretory pathway, possibly mediating retrograde transport form cis-golgi membrane to the ER.
Alternative Names: Syntaxin-8, STX8

Molecular Weight: 24.6 kDa

UniProt: Q9UNK0

Pathways: Synaptic Vesicle Exocytosis