ASB13 Protein (AA 1-278) (His tag)
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- Target See all ASB13 Proteins
- ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-278
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ASB13 protein is labelled with His tag.
- Purpose
- Recombinant Human Ankyrin Repeat and SOCS Box Protein 13/ASB13 (N-6His)
- Sequence
- MNHKVHHHHH HMEPRAADGC FLGDVGFWVE RTPVHEAAQR GESLQLQQLI ESGACVNQVT VDSITPLHAA SLQGQARCVQ LLLAAGAQVD ARNIDGSTPL CDACASGSIE CVKLLLSYGA KVNPPLYTAS PLHEACMSGS SECVRLLIDV GANLEAHDCH FGTPLHVACA REHLDCVKVL LNAGANVNAA KLHETALHHA AKVKNVDLIE MLIEFGGNIY ARDNRGKKPS DYTWSSSAPA KCFEYYEKTP LTLSQLCRVN LRKATGVRGL EKIAKLNIPP RLIDYLSYN
- Characteristics
- Recombinant Human Ankyrin repeat and SOCS box protein 13/ASB13 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Asn278) of Human ASB13 fused with a 6His tag at the N-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ASB13 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of PBS, pH 7.4, 4M Urea.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- ASB13 (Ankyrin Repeat and SOCS Box Containing 13 (ASB13))
- Alternative Name
- ASB13 (ASB13 Products)
- Synonyms
- 2210015B19Rik Protein, 6430573K02Rik Protein, Asb-13 Protein, C85285 Protein, ankyrin repeat and SOCS box-containing 13 Protein, ankyrin repeat and SOCS box containing 13 Protein, Asb13 Protein, ASB13 Protein
- Sub Type
- Fusionprotein
- Background
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Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alternative Names: Ankyrin repeat and SOCS box protein 13, ASB13, - Molecular Weight
- 31.4 kDa
- UniProt
- Q8WXK3
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