Ccl21a Protein (AA 24-133)

Catalog No. ABIN1692325

Product Details

Target: Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

Protein Type: Recombinant

Protein Characteristics: AA 24-133

Origin: Mouse

Source: Escherichia coli (E. coli)

Purpose: Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine

Sequence: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG

Characteristics:

Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

Alternative Name: C-C Motif Chemokine 21a/CCL21a (CCL21A Products)

Synonyms: 6CKBAC2 Protein, 6Ckine Protein, ALP Protein, AW987545 Protein, CKb9 Protein, SCYA21a Protein, SLC Protein, Scya21 Protein, Scya21b Protein, Tca4 Protein, plt Protein, chemokine (C-C motif) ligand 21A (serine) Protein, Ccl21a Protein

Background: Recombinant Mouse C-C Motif Chemokine 21a/CCL21a is produced with our E. coli expression system. The target protein is expressed with sequence (Ser24-Gly133) of Mouse CCL21a.
C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine β (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 AA residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.

Molecular Weight: 12 kDa

UniProt: P84444