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Ccl21a Protein (AA 24-133)

CCL21A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1692325
  • Target See all Ccl21a (CCL21A) Proteins
    Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 24-133
    Origin
    Mouse
    Source
    • 3
    Escherichia coli (E. coli)
    Purpose
    Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine
    Sequence
    SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FSPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG
    Characteristics

    Recombinant Mouse C-C Motif Chemokine 21a/CCL21a//6Ckine

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CCL21A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))
    Alternative Name
    C-C Motif Chemokine 21a/CCL21a (CCL21A Products)
    Synonyms
    6CKBAC2 Protein, 6Ckine Protein, ALP Protein, AW987545 Protein, CKb9 Protein, SCYA21a Protein, SLC Protein, Scya21 Protein, Scya21b Protein, Tca4 Protein, plt Protein, chemokine (C-C motif) ligand 21A (serine) Protein, Ccl21a Protein
    Background
    Recombinant Mouse C-C Motif Chemokine 21a/CCL21a is produced with our E. coli expression system. The target protein is expressed with sequence (Ser24-Gly133) of Mouse CCL21a.
    C-C Motif Chemokine 21a (CCL21a) is a small secreted cytokine that belongs to the intercrine β (CC chemokine) family. Mouse CCL21 cDNA encodes a 133 AA residue protein with a 23 residue signal peptide that is cleaved to generate the 110 residue mature protein. Mouse CCL21 has three forms while CCL21a has Ser-65. CCL21 elicits its effects by binding to a cell surface chemokine receptor known as CCR7 and CXCR3. Mouse CCL21 inhibits hemopoiesis and stimulates chemotaxis. It has chemotactic function in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Mouse CCL21 shows preferential activity towards naive T-cells and may play a role in mediating homing of lymphocytes to secondary lymphoid organs.
    Molecular Weight
    12 kDa
    UniProt
    P84444
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