Peroxiredoxin 3 Protein (PRDX3) (AA 63-256)
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- Target See all Peroxiredoxin 3 (PRDX3) Proteins
- Peroxiredoxin 3 (PRDX3)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 63-256
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Peroxiredoxin-3/PRDX3
- Sequence
- MPAVTQHAPY FKGTAVVNGE FKDLSLDDFK GKYLVLFFYP LDFTFVCPTE IVAFSDKANE FHDVNCEVVA VSVDSHFSHL AWINTPRKNG GLGHMNIALL SDLTKQISRD YGVLLEGSGL ALRGLFIIDP NGVIKHLSVN DLPVGRSVEE TLRLVKAFQY VETHGEVCPA NWTPDSPTIK PSPAASKEYF QKVNQ
- Characteristics
- Recombinant Human Thioredoxin-Dependent Peroxide Reductase Mitochondrial/PRDX3 is produced with our E. coli expression system. The target protein is expressed with sequence (Pro63-Gln256) of Human PRDX3.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product PRDX3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- Peroxiredoxin 3 (PRDX3)
- Alternative Name
- PRDX3 (PRDX3 Products)
- Synonyms
- cb718 Protein, wu:fk49e09 Protein, zgc:110282 Protein, zgc:112512 Protein, MGC83969 Protein, PRDX3 Protein, AOP-1 Protein, AOP1 Protein, HBC189 Protein, MER5 Protein, PRO1748 Protein, SP-22 Protein, prx-III Protein, AW822249 Protein, Aop1 Protein, D0Tohi1 Protein, Ef2l Protein, Mer5 Protein, Prx3 Protein, SP22 Protein, TDXM Protein, MTAP Protein, peroxiredoxin 3 Protein, peroxiredoxin 3 S homeolog Protein, peroxiredoxin PRX3 Protein, prdx3 Protein, PRDX3 Protein, prdx3.S Protein, PRX3 Protein, Prdx3 Protein
- Background
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Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Alternative Names: Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Antioxidant Protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1 - Molecular Weight
- 21.6 kDa
- UniProt
- P30048
- Pathways
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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