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Peroxiredoxin 3 Protein (PRDX3) (AA 63-256)

PRDX3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1692321
  • Target See all Peroxiredoxin 3 (PRDX3) Proteins
    Peroxiredoxin 3 (PRDX3)
    Protein Type
    Recombinant
    Protein Characteristics
    AA 63-256
    Origin
    • 5
    • 2
    • 2
    • 1
    • 1
    Human
    Source
    • 7
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Peroxiredoxin-3/PRDX3
    Sequence
    MPAVTQHAPY FKGTAVVNGE FKDLSLDDFK GKYLVLFFYP LDFTFVCPTE IVAFSDKANE FHDVNCEVVA VSVDSHFSHL AWINTPRKNG GLGHMNIALL SDLTKQISRD YGVLLEGSGL ALRGLFIIDP NGVIKHLSVN DLPVGRSVEE TLRLVKAFQY VETHGEVCPA NWTPDSPTIK PSPAASKEYF QKVNQ
    Characteristics
    Recombinant Human Thioredoxin-Dependent Peroxide Reductase Mitochondrial/PRDX3 is produced with our E. coli expression system. The target protein is expressed with sequence (Pro63-Gln256) of Human PRDX3.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product PRDX3 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    -80 °C
    Storage Comment
    Store at < -20°C, stable for 6 months after receipt.
    Please minimize freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Peroxiredoxin 3 (PRDX3)
    Alternative Name
    PRDX3 (PRDX3 Products)
    Synonyms
    cb718 Protein, wu:fk49e09 Protein, zgc:110282 Protein, zgc:112512 Protein, MGC83969 Protein, PRDX3 Protein, AOP-1 Protein, AOP1 Protein, HBC189 Protein, MER5 Protein, PRO1748 Protein, SP-22 Protein, prx-III Protein, AW822249 Protein, Aop1 Protein, D0Tohi1 Protein, Ef2l Protein, Mer5 Protein, Prx3 Protein, SP22 Protein, TDXM Protein, MTAP Protein, peroxiredoxin 3 Protein, peroxiredoxin 3 S homeolog Protein, peroxiredoxin PRX3 Protein, prdx3 Protein, PRDX3 Protein, prdx3.S Protein, PRX3 Protein, Prdx3 Protein
    Background
    Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
    Alternative Names: Thioredoxin-Dependent Peroxide Reductase Mitochondrial, Antioxidant Protein 1, AOP-1, HBC189, Peroxiredoxin III, Prx-III, Peroxiredoxin-3, Protein MER5 homolog, PRDX3, AOP1
    Molecular Weight
    21.6 kDa
    UniProt
    P30048
    Pathways
    Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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