CTH Protein (AA 1-405)
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- Target See all CTH Proteins
- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-405
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Recombinant Human Cystathionine γ-Lyase/CTH
- Sequence
- GHMQEKDASS QGFLPHFQHF ATQAIHVGQD PEQWTSRAVV PPISLSTTFK QGAPGQHSGF EYSRSGNPTR NCLEKAVAAL DGAKYCLAFA SGLAATVTIT HLLKAGDQII CMDDVYGGTN RYFRQVASEF GLKISFVDCS KIKLLEAAIT PETKLVWIET PTNPTQKVID IEGCAHIVHK HGDIILVVDN TFMSPYFQRP LALGADISMY SATKYMNGHS DVVMGLVSVN CESLHNRLRF LQNSLGAVPS PIDCYLCNRG LKTLHVRMEK HFKNGMAVAQ FLESNPWVEK VIYPGLPSHP QHELVKRQCT GCTGMVTFYI KGTLQHAEIF LKNLKLFTLA ESLGGFESLA ELPAIMTHAS VLKNDRDVLG ISDTLIRLSV GLEDEEDLLE DLDQALKAAH PPSGSHS
- Characteristics
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Recombinant Human Cystathionine γ-Lyase/CTH
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CTH Protein
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Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) protein (GST tag)
CTH Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) protein (His-IF2DI Tag)CTH Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Cystathionase (Cystathionine gamma-Lyase) (CTH) (AA 1-405) protein (His tag)CTH Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Cystathionase (Cystathionine gamma-Lyase) (CTH) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)CTH Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Cystathionase (Cystathionine gamma-Lyase) (CTH) proteinCTH Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % ELISA, WB, SDS, IP
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl,20 % Glycerol, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))
- Alternative Name
- Cystathionine gamma-Lyase/CTH (CTH Products)
- Background
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Recombinant Human Cystathionine γ-Lyase/CTH is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser405) of Human CTH.
Cystathionine γ-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine. - Molecular Weight
- 44.7kDa
- UniProt
- P32929
- Pathways
- ER-Nucleus Signaling, Warburg Effect
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