UBE2B Protein (AA 1-152)

Catalog No. ABIN1692121

Product Details

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Protein Type: Recombinant

Protein Characteristics: AA 1-152

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Ubiquitin-Conjugating Enzyme E2 B/UBE2B/HR6B

Sequence: GSHMSTPARR RLMRDFKRLQ EDPPVGVSGA PSENNIMQWN AVIFGPEGTP FEDGTFKLVI EFSEEYPNKP PTVRFLSKMF HPNVYADGSI CLDILQNRWS PTYDVSSILT SIQSLLDEPN PNSPANSQAA QLYQENKREY EKRVSAIVEQ SWNDS

Characteristics:

Recombinant Human Ubiquitin-Conjugating Enzyme E2 B/UBE2B/HR6B

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 10 mM HEPES, pH 7.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: UBE2B (Ubiquitin-Conjugating Enzyme E2B (UBE2B))

Alternative Name: Ubiquitin-Conjugating Enzyme E2 B/UBE2B (UBE2B Products)

Synonyms: E2-17kDa Protein, HHR6B Protein, HR6B Protein, RAD6B Protein, UBC2 Protein, e2-17kda Protein, hhr6b Protein, hr6b Protein, rad6b Protein, ubc2 Protein, zgc:100921 Protein, 2610301N02Rik Protein, E2-14k Protein, Rad6b Protein, mHR6B Protein, ubiquitin conjugating enzyme E2 B Protein, ubiquitin-conjugating enzyme E2B Protein, ubiquitin-conjugating enzyme E2B (RAD6 homolog) Protein, ubiquitin conjugating enzyme E2 B S homeolog Protein, UBE2B Protein, Ube2b Protein, ube2b Protein, ube2b.S Protein

Target Type: Viral Protein

Background: Recombinant Human Ubiquitin-Conjugating Enzyme E2 B/UBE2B is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser152) of Human UBE2B.
Ubiquitin-Conjugating Enzyme E2 B (UBE2B) belongs to the ubiquitin-conjugating enzyme family. UBE2B can catalyze the covalent attachment of ubiquitin to other proteins, and is essential for the multi-ubiquitination and degradation of N-end rule substrates. UBE2B is indispensability for postreplication repair of UV-damaged DNA and may be involved in neurite outgrowth.Additionally, UBE2B may have a role in sepsis-induced muscle protein proteolysis and cancer-induced cachexia.

Molecular Weight: 17.5 kDa

UniProt: P63146