CCL18 Protein (AA 21-89) (His tag)
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- Target See all CCL18 Proteins
- CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-89
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CCL18 protein is labelled with His tag.
- Purpose
- Recombinant Human C-C Motif Chemokine 18/CCL18/PARC (N-6His)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MAQVGTNKEL CCLVYTSWQI PQKFIVDYSE TSPQCPKPGV ILLTKRGRQI CADPNKKWVQ KYISDLKLNA
- Characteristics
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Recombinant Human C-C Motif Chemokine 18/CCL18/PARC (N-6His)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CCL18 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
- Alternative Name
- C-C Motif Chemokine 18/CCL18 (CCL18 Products)
- Background
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Recombinant Human C-C Motif Chemokine 18/CCL18 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala21-Ala89) of Human CCL18 fused with a 6His tag at the N-terminus.
C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine β (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses. - Molecular Weight
- 10.1 kDa
- UniProt
- P55774
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