TPM3 Protein (AA 1-248)

Catalog No. ABIN1691997

Product Details

Target: TPM3 (Tropomyosin 3 (TPM3))

Protein Type: Recombinant

Protein Characteristics: AA 1-248

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Tropomyosin α-3 Chain/TPM3

Sequence: MAGITTIEAV KRKIQVLQQQ ADDAEERAER LQREVEGERR AREQAEAEVA SLNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRALK DEEKMELQEI QLKEAKHIAE EADRKYEEVA RKLVIIEGDL ERTEERAELA ESRCREMDEQ IRLMDQNLKC LSAAEEKYSQ KEDKYEEEIK ILTDKLKEAE TRAEFAERSV AKLEKTIDDL EDKLKCTKEE HLCTQRMLDQ TLLDLNEM

Characteristics: Recombinant Human Tropomyosin Alpha-3 Chain/TPM3 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Met248) of Human TPM3.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: TPM3 (Tropomyosin 3 (TPM3))

Alternative Name: TPM3 (TPM3 Products)

Synonyms: CAPM1 Protein, CFTD Protein, NEM1 Protein, OK/SW-cl.5 Protein, TM-5 Protein, TM3 Protein, TM30 Protein, TM30nm Protein, TM5 Protein, TPMsk3 Protein, TRK Protein, hscp30 Protein, cb674 Protein, fa17b11 Protein, fb83b01 Protein, fk41e01 Protein, hm:zeh0298 Protein, wu:fa17b11 Protein, wu:fb83b01 Protein, wu:fk41e01 Protein, zeh0298 Protein, zgc:77592 Protein, TPM3 Protein, Tm5NM Protein, Tpm-5 Protein, Tpm5 Protein, Trop-5 Protein, gamma-TM Protein, hTM30nm Protein, hTMnm Protein, tm3 Protein, tpm3 Protein, tpm3.L Protein, tropomyosin 3 Protein, tropomyosin 3, gamma Protein, tropomyosin 3 S homeolog Protein, TPM3 Protein, tpm3 Protein, Tpm3 Protein, tpm3.S Protein

Background: Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.
Alternative Names: Tropomyosin Alpha-3 Chain, Gamma-Tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5, TPM3

Molecular Weight: 29 kDa