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TPM3 Protein (AA 1-248)

TPM3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691997
  • Target See all TPM3 Proteins
    TPM3 (Tropomyosin 3 (TPM3))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-248
    Origin
    • 9
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 6
    • 4
    • 2
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Tropomyosin α-3 Chain/TPM3
    Sequence
    MAGITTIEAV KRKIQVLQQQ ADDAEERAER LQREVEGERR AREQAEAEVA SLNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIENRALK DEEKMELQEI QLKEAKHIAE EADRKYEEVA RKLVIIEGDL ERTEERAELA ESRCREMDEQ IRLMDQNLKC LSAAEEKYSQ KEDKYEEEIK ILTDKLKEAE TRAEFAERSV AKLEKTIDDL EDKLKCTKEE HLCTQRMLDQ TLLDLNEM
    Characteristics
    Recombinant Human Tropomyosin Alpha-3 Chain/TPM3 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Met248) of Human TPM3.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product TPM3 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    TPM3 (Tropomyosin 3 (TPM3))
    Alternative Name
    TPM3 (TPM3 Products)
    Synonyms
    CAPM1 Protein, CFTD Protein, NEM1 Protein, OK/SW-cl.5 Protein, TM-5 Protein, TM3 Protein, TM30 Protein, TM30nm Protein, TM5 Protein, TPMsk3 Protein, TRK Protein, hscp30 Protein, cb674 Protein, fa17b11 Protein, fb83b01 Protein, fk41e01 Protein, hm:zeh0298 Protein, wu:fa17b11 Protein, wu:fb83b01 Protein, wu:fk41e01 Protein, zeh0298 Protein, zgc:77592 Protein, TPM3 Protein, Tm5NM Protein, Tpm-5 Protein, Tpm5 Protein, Trop-5 Protein, gamma-TM Protein, hTM30nm Protein, hTMnm Protein, tm3 Protein, tpm3 Protein, tpm3.L Protein, tropomyosin 3 Protein, tropomyosin 3, gamma Protein, tropomyosin 3 S homeolog Protein, TPM3 Protein, tpm3 Protein, Tpm3 Protein, tpm3.S Protein
    Background
    Tropomyosin Alpha-3 Chain (TPM3) is a member of the Tropomyosin family. TPM3 exists as a heterodimer consisting of an alpha and a beta chain. TPM3 plays a central role in association with the Troponin complex and in the calcium dependent regulation of vertebrate striated muscle contraction. Defects in TPM3 are the cause of thyroid papillary carcinoma. Mutations in the TPM3 gene cause autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are linked with cancer.
    Alternative Names: Tropomyosin Alpha-3 Chain, Gamma-Tropomyosin, Tropomyosin-3, Tropomyosin-5, hTM5, TPM3
    Molecular Weight
    29 kDa
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