MAP1LC3A Protein (AA 1-121) (His tag)
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- Target See all MAP1LC3A Proteins
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-121
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MAP1LC3A protein is labelled with His tag.
- Purpose
- Recombinant Human Microtubule-Associated Protein 1 Light Chain 3 α/MAP1LC3A (C-6His)
- Sequence
- MPSDRPFKQR RSFADRCKEV QQIRDQHPSK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELVKIIRRR LQLNPTQAFF LLVNQHSMVS VSTPIADIYE QEKDEDGFLY MVYASQETFG FLEHHHHHH
- Characteristics
- Recombinant Human Microtubule-Associated Proteins 1A/1B Light Chain 3A/MAP1LC3A is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Phe121) of Human MAP1LC3A fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product MAP1LC3A Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 20 % Glycerol, 0.1M NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
- Alternative Name
- MAP1LC3A (MAP1LC3A Products)
- Synonyms
- ATG8E Protein, LC3 Protein, LC3A Protein, MAP1ALC3 Protein, MAP1BLC3 Protein, 1010001H21Rik Protein, 4922501H04Rik Protein, LC3a Protein, MGC69006 Protein, zgc:77094 Protein, MGC89867 Protein, MAP1LC3A Protein, map1lc3a Protein, microtubule associated protein 1 light chain 3 alpha Protein, microtubule-associated protein 1 light chain 3 alpha Protein, microtubule associated protein 1 light chain 3 alpha S homeolog Protein, MAP1LC3A Protein, Map1lc3a Protein, map1lc3a.S Protein, map1lc3a Protein
- Sub Type
- Fusionprotein
- Background
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Microtubule-Associated Proteins 1A/1B Light Chain 3A (MAP1LC3A) belongs to the MAP1 LC3 family. MAP1LC3A is found most abundantly in the heart, brain, liver, skeletal muscle, and testis. But it is absent in the thymus and peripheral blood leukocytes. MAP1LC3A is thought to take part in the formation of autophagosomal vacuoles and is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. In addition, MAP1A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity.
Alternative Names: Microtubule-Associated Proteins 1A/1B Light Chain 3A, Autophagy-Related Protein LC3 A, Autophagy-Related Ubiquitin-Like Modifier LC3 A, MAP1 Light Chain 3-Like Protein 1, MAP1A/MAP1B Light Chain 3 A, MAP1A/MAP1B LC3 A, Microtubule-Associated Protein 1 Lig - Molecular Weight
- 15.3 kDa
- UniProt
- Q9H492
- Pathways
- Autophagy
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