ULBP2 Protein (AA 26-217) (Fc Tag)
-
- Target See all ULBP2 Proteins
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-217
- Origin
- Human
-
Source
- Human Cells
- Purification tag / Conjugate
- This ULBP2 protein is labelled with Fc Tag.
- Purpose
- Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc)
- Sequence
- GRADPHSLCY DITVIPKFRP GPRWCAVQGQ VDEKTFLHYD CGNKTVTPVS PLGKKLNVTT AWKAQNPVLR EVVDILTEQL RDIQLENYTP KEPLTLQARM SCEQKAEGHS SGSWQFSFDG QIFLLFDSEK RMWTTVHPGA RKMKEKWEND KVVAMSFHYF SMGDCIGWLE DFLMGMDSTL EPSAGAPLAM SSVDDIEGRM DEPKSCDKTH TCPPCPAPEL LGGPSVFLFP PKPKDTLMIS RTPEVTCVVV DVSHEDPEVK FNWYVDGVEV HNAKTKPREE QYNSTYRVVS VLTVLHQDWL NGKEYKCKVS NKALPAPIEK TISKAKGQPR EPQVYTLPPS REEMTKNQVS LTCLVKGFYP SDIAVEWESN GQPENNYKTT PPVLDSDGSF FLYSKLTVDK SRWQQGNVFS CSVMHEALHN HYTQKSLSLS PGK
- Characteristics
-
Recombinant Human NKG2D Ligand 2/NKG2DL2/N2DL2 (C-Fc)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product ULBP2 Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
-
- Target
- ULBP2 (UL16 Binding Protein 2 (ULBP2))
- Alternative Name
- NKG2D Ligand 2/N2DL2 (ULBP2 Products)
- Synonyms
- N2DL2 Protein, RAET1H Protein, UL16 binding protein 2 Protein, NKG2D ligand 2-like Protein, ULBP2 Protein, LOC100355436 Protein
- Background
-
Recombinant Human NKG2D Ligand 2/N2DL2 is produced by our mammalian expression system. The target protein is expressed with sequence (Gly26-Ser217) of Human ULBP-2 fused with a FC tag at the C-terminus.
NKG2D Ligand 2 (N2DL2) is a member of a family of cell-surface proteins. N2DL2 function as ligands for human cytomegalovirus glycoprotein UL16. N2DL2 is anchored to the membrane via a GPI-linkage. N2DL2 is bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, T cells. Engagement of NKG2D results in the activation of cytolytic activity and cytokine production by these effects cells. The ULBPs are expressed on some tumor cells and have been implicated in tumor surveillance. - Molecular Weight
- 51.4 kDa
- UniProt
- Q9BZM5
-