LILRA2 Protein (AA 24-420) (His tag)

Catalog No. ABIN1691428

Product Details

Target: LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))

Protein Type: Recombinant

Protein Characteristics: AA 24-420

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This LILRA2 protein is labelled with His tag.

Purpose: Recombinant Human Leukocyte Ig-Like Receptor A2/LILRA2/ILT1/CD85h (C-6His)

Sequence: GHLPKPTLWA EPGSVIIQGS PVTLRCQGSL QAEEYHLYRE NKSASWVRRI QEPGKNGQFP IPSITWEHAG RYHCQYYSHN HSSEYSDPLE LVVTGAYSKP TLSALPSPVV TLGGNVTLQC VSQVAFDGFI LCKEGEDEHP QRLNSHSHAR GWSWAIFSVG PVSPSRRWSY RCYAYDSNSP YVWSLPSDLL ELLVPGVSKK PSLSVQPGPM VAPGESLTLQ CVSDVGYDRF VLYKEGERDF LQRPGWQPQA GLSQANFTLG PVSPSHGGQY RCYSAHNLSS EWSAPSDPLD ILITGQFYDR PSLSVQPVPT VAPGKNVTLL CQSRGQFHTF LLTKEGAGHP PLHLRSEHQA QQNQAEFRMG PVTSAHVGTY RCYSSLSSNP YLLSLPSDPL ELVVSASVDH HHHHH

Characteristics: Recombinant Human Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2/LILRA2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gly24-Ser420) of Human LILRA2 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))

Alternative Name: ILT1 (LILRA2 Products)

Synonyms: CD85H Protein, ILT1 Protein, LIR-7 Protein, LIR7 Protein, leukocyte immunoglobulin like receptor A2 Protein, LILRA2 Protein

Sub Type: Fusionprotein

Background: Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2 (LILRA2) is a single-pass type I membrane protein. LILRA2 is expressed predominantly on monocytes and B cells, and at lower levels on dendritic cells and natural killer cells. LILRA2 contains four Ig-like C2-type domains, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. LILRA2 does not bind class I MHC antigens.
Alternative Names: Leukocyte Immunoglobulin-Like Receptor Subfamily A Member 2, CD85 Antigen-Like Family Member H, Immunoglobulin-Like Transcript 1, ILT-1, Leukocyte Immunoglobulin-Like Receptor 7, LIR-7, CD85h, LILRA2, ILT1, LIR7

Molecular Weight: 44.8 kDa

UniProt: Q8N149