nectin-3 Protein (C-Term, Extracellular Domain)
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- Target See all nectin-3 (NECTIN3) Proteins
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- C-Term, Extracellular Domain
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Origin
- Human
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Source
- HEK-293T Cells
- Specificity
- Optimized DNA sequence encoding extracellular domain of human CD113 (nectin-3) including a C-terminal 6His tag was expressed in HEK293 cells.
- Characteristics
- Recombinant CD113 (nectin-3) is a monomer protein consisting of 354 amino acid residue subunits, due to glycosylation migrates as an approximately 70 kDa protein on SDS-PAGE.
- Purity
- > 95 %, as determined by SDS-PAGE and HPLC
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
- Top Product
- Discover our top product NECTIN3 Protein
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- Comment
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The activity of Recombinant human CD113 was measured in a functional ELISA assay, immobilized recombinant human CD113 at 1 µg/mL ( 100 µL/well ) can bind biotinylated Nectin-1 with a linear range of 6 - 800 µg/mL
- Restrictions
- For Research Use only
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- Buffer
- PBS solution, pH7.2.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Recombinant rat PDGFRb as supplied, can be stored in working aliquots at - 8 °C for one month, or at -20 °C to -70 °C for twelve months.
- Expiry Date
- 12 months
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- Target
- nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))
- Alternative Name
- CD113 (NECTIN3 Products)
- Synonyms
- PVRL3 Protein, CD113 Protein, CDW113 Protein, NECTIN-3 Protein, PPR3 Protein, PRR3 Protein, PVRR3 Protein, 2610301B19Rik Protein, 3000002N23Rik Protein, 4921513D19Rik Protein, AA407785 Protein, AU016832 Protein, AW538082 Protein, nectin cell adhesion molecule 3 Protein, poliovirus receptor-related 3 Protein, Nectin3 Protein, NECTIN3 Protein, PVRL3 Protein, nectin3 Protein
- Background
- The PDGFR/PDGF system includes two receptors (PDGFRA and PDGFRB) and four ligands (PDGFA, PDGFB, PDGFC, and PDGFD).
- UniProt
- Q9NQS3
- Pathways
- Cell-Cell Junction Organization
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