IL17RC Protein (C-Term, Extracellular Domain)
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- Target See all IL17RC Proteins
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Protein Type
- Recombinant
- Protein Characteristics
- C-Term, Extracellular Domain
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Origin
- Human
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Source
- HEK-293T Cells
- Specificity
- Optimized DNA sequence encoding extracellular domain of human IL-17RC receptor including a C terminal Human IgG1 Fc tag was expressed in HEK293 cells.
- Characteristics
- Recombinant IL17RC-Fc is a homodimer protein consisting of 675 amino acid residue subunits, due to glycosylation migrates as an approximately 100kD protein under reducing SDS-PAGE conditions.
- Purity
- > 98 %, as determined by SDS-PAGE and HPLC
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
- Top Product
- Discover our top product IL17RC Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS solution, pH7.2
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
- Expiry Date
- 12-24 months
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- Target
- IL17RC (Interleukin 17 Receptor C (IL17RC))
- Alternative Name
- IL17RC (IL17RC Products)
- Synonyms
- IL17-RL Protein, IL17RL Protein, 1110025H02Rik Protein, Gm19850 Protein, IL-17RC Protein, IL17-RC Protein, Il17rl Protein, interleukin 17 receptor C Protein, Il17rc Protein, IL17RC Protein
- Background
- Common gamma chain Interleukin (IL)-2, IL-4, IL-7, IL-9 and IL-15 belong to a family of cytokines whose receptors share the common gamma chain (gamma c). Despite some redundancy, thesecytokines that signal through the gamma c (gamma c cytokines) have essentially distinct and oftencritical effects in normal T-cell development, survival, proliferation and differentiation. Importantly, they have also been implicated,directly or indirectly, in T-cell leukemogenesis.
- UniProt
- Q8NAC3
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