LGALS1/Galectin 1 Protein
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- Target See all LGALS1/Galectin 1 (LGALS1) Proteins
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purpose
- Galectin-1
- Sequence
- ACGLVASNLN LKPGECLRVR GEVAPDAKSF VLNLGKDSNN LCLHFNPRFN AHGDANTIVC NSKDGGAWGT EQREAVFPF QPGSVAEVCI T FDQANLTVKL PDGYEFKFPN RLNLEAINYM AADGDFKIKC VAFDLEHHHH HH
- Specificity
- Chromosomal location:22q13.1
- Characteristics
- Length (aa):142
- Purity
- > 98 % by SDS-PAGE and visualized by Coomassie stain
- Top Product
- Discover our top product LGALS1 Protein
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- Comment
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Cytokines & Growth Factors
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge vial prior to opening. Human Galectin-1 should be reconstituted in water to a concentration of 0.1 mg/mL. This solution can be diluted in water or other buffer solutions or stored at -20 °C.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- RT,0 °C,-20 °C
- Storage Comment
- The lyophilized human Galectin-1, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted human Galectin-1 should be stored in working aliquots at -20°C.
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- Target
- LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))
- Alternative Name
- Galectin-1 (LGALS1 Products)
- Synonyms
- GAL1 Protein, GBP Protein, Galectin-1 Protein, LGAS1 Protein, LGALS1 Protein, MGC64502 Protein, GB10026 Protein, AA410090 Protein, Gal-1 Protein, Galbp Protein, L-14.5 Protein, L14 Protein, Lect14 Protein, galectin-1 Protein, Galaptin Protein, galectin 1 Protein, galectin-1 Protein, lectin, galactoside-binding, soluble, 1 L homeolog Protein, protein enabled Protein, lectin, galactose binding, soluble 1 Protein, LGALS1 Protein, Lgals1 Protein, CC1G_05003 Protein, CC1G_05004 Protein, lgals1.L Protein, LOC408848 Protein
- Background
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Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.
Synonyms: LGALS1, GBP, GAL1 - Molecular Weight
- 14,5 kDa
- Gene ID
- 3956
- NCBI Accession
- NM_002305, NP_002296
- UniProt
- P09382
- Pathways
- Carbohydrate Homeostasis
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