EGFL7 Protein (His tag)
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- Target See all EGFL7 Proteins
- EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Insect Cells
- Purification tag / Conjugate
- This EGFL7 protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Purpose
- VE-Statin/EGFL7
- Sequence
- HHHHHHTEHA YRRSPGLAPA RPRYACCPGW KRTSGLPGAC GAAICQPPCR NGGSCVQPGR CRCPAGWRGD TCQSDVDECS ARRGGCPQRC VNTAGSYWCQ CWEGHSLSAD GTLCVPKGGP PRVAPNPTGV DSAMKEEVQR LQSRVDLLEE KLQLVLAPLH SLASQALEHG LPDPGSLLVH SFQQLGRIDS LSEQISFLEE QLGSCSCKKD S
- Specificity
- Chromosomal location:9q34.3
- Characteristics
- Length (aa):211
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product EGFL7 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Cytokines & Growth Factors
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- The lyophilized human EGFL7 should be reconstituted in water to a concentration of not lower than 50 μg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Lyophilized samples are stable for greater than six months at -20°C to -70°C. Reconstituted EGFL7 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles!
- Expiry Date
- 6 months
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- Target
- EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))
- Alternative Name
- VE-Statin/EGFL7 (EGFL7 Products)
- Synonyms
- egfl7 Protein, MGC53105 Protein, EGFL7 Protein, zgc:136669 Protein, zgc:152804 Protein, zneu1 Protein, xegfl7 Protein, MGC147423 Protein, VE-statin Protein, Zneu1 Protein, NEU1 Protein, RP11-251M1.2 Protein, VE-STATIN Protein, ZNEU1 Protein, EGF like domain multiple 7 S homeolog Protein, EGF like domain multiple 7 Protein, EGF-like-domain, multiple 7 Protein, EGF-like domain 7 Protein, egfl7.S Protein, EGFL7 Protein, egfl7 Protein, Egfl7 Protein
- Background
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EGFL7 (VE-Statin) is an ∼ 30 kDa secreted protein that contains an Emilin-like (EMI) domain (a multimerization motif), and two epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
Synonyms: EGFL7, NEU1, ZNEU1, VE-STATIN, RP11-251M1.2 - Molecular Weight
- 22.75 kDa
- Gene ID
- 51162
- NCBI Accession
- NM_016215, NP_057299
- UniProt
- Q9UHF1
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