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PROX1 Protein (partial)

PROX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS-PAGE WB Active
Catalog No. ABIN1589681
  • Target See all PROX1 Proteins
    PROX1 (Prospero Homeobox 1 (PROX1))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    partial
    Origin
    • 4
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    Western Blotting (WB)
    Purpose
    Prox-1 (fragment)
    Sequence
    MAEGLSLSLI KSECGDLQDM SEISPYSGSA MQEGLSPNHL KKAKLMFFYT RYPSSNMLKT YFSDVKFNRC ITSQLIKWFS NFREFYYIQM EKYARQAIND GVTSTEELSI TRDCELYRAL NMHYNKANDF EVPERFLEVA QITLREFFNA IIAGKDVDPS WKKAIYKVIC KLDSEVPEIF KSPNCLQELL HE
    Specificity
    Chromosomal location:1q32.2-q32.3
    Characteristics
    Length (aa):192
    Purity
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product PROX1 Protein
  • Application Notes
    Control for Western Blotting. Biological activity not tested.
    Comment

    Cytokines & Growth Factors

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge vial prior to opening. The lyophilized Prox-1 should be reconstituted in water to a concentration not lower than 50 μg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    RT,-20 °C
    Storage Comment
    The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted Prox-1 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
  • Target
    PROX1 (Prospero Homeobox 1 (PROX1))
    Alternative Name
    Prox-1 (PROX1 Products)
    Synonyms
    xprox1 Protein, prospero Protein, PROX1 Protein, LOC100232600 Protein, A230003G05Rik Protein, prox1 Protein, zgc:111888 Protein, prospero homeobox 1 Protein, prospero homeobox 1 L homeolog Protein, prospero homeobox 1a Protein, PROX1 Protein, prox1.L Protein, prox1 Protein, Prox1 Protein, prox1a Protein
    Background
    Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. The highly conserved C-terminal part of the homeobox transcription factor Prox1 was produced in E. coli. It was not tested for activity and can be used as positive control e.g. in Western analysis.
    Synonyms: PROX1, W117m
    Molecular Weight
    22.35 kDa
    Gene ID
    5629
    NCBI Accession
    NM_002763, NP_002754
    UniProt
    Q92786
    Pathways
    Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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