PROX1 Protein (partial)
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- Target See all PROX1 Proteins
- PROX1 (Prospero Homeobox 1 (PROX1))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Western Blotting (WB)
- Purpose
- Prox-1 (fragment)
- Sequence
- MAEGLSLSLI KSECGDLQDM SEISPYSGSA MQEGLSPNHL KKAKLMFFYT RYPSSNMLKT YFSDVKFNRC ITSQLIKWFS NFREFYYIQM EKYARQAIND GVTSTEELSI TRDCELYRAL NMHYNKANDF EVPERFLEVA QITLREFFNA IIAGKDVDPS WKKAIYKVIC KLDSEVPEIF KSPNCLQELL HE
- Specificity
- Chromosomal location:1q32.2-q32.3
- Characteristics
- Length (aa):192
- Purity
- > 95 % by SDS-PAGE
- Top Product
- Discover our top product PROX1 Protein
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Prospero Homeobox 1 (PROX1) (AA 354-737) protein (His tag)
PROX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Prospero Homeobox 1 (PROX1) (AA 547-737) protein (His tag)PROX1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Prospero Homeobox 1 (PROX1) (AA 638-737) protein (GST tag)PROX1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
- Control for Western Blotting. Biological activity not tested.
- Comment
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Cytokines & Growth Factors
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge vial prior to opening. The lyophilized Prox-1 should be reconstituted in water to a concentration not lower than 50 μg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- RT,-20 °C
- Storage Comment
- The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted Prox-1 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
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- Target
- PROX1 (Prospero Homeobox 1 (PROX1))
- Alternative Name
- Prox-1 (PROX1 Products)
- Synonyms
- xprox1 Protein, prospero Protein, PROX1 Protein, LOC100232600 Protein, A230003G05Rik Protein, prox1 Protein, zgc:111888 Protein, prospero homeobox 1 Protein, prospero homeobox 1 L homeolog Protein, prospero homeobox 1a Protein, PROX1 Protein, prox1.L Protein, prox1 Protein, Prox1 Protein, prox1a Protein
- Background
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Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells. The highly conserved C-terminal part of the homeobox transcription factor Prox1 was produced in E. coli. It was not tested for activity and can be used as positive control e.g. in Western analysis.
Synonyms: PROX1, W117m - Molecular Weight
- 22.35 kDa
- Gene ID
- 5629
- NCBI Accession
- NM_002763, NP_002754
- UniProt
- Q92786
- Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
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