CD11b Protein (AA 1-126) (His tag)

Catalog No. ABIN1461847

Product Details

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Protein Type: Recombinant

Protein Characteristics: AA 1-126

Origin: Guinea Pig

Source: Yeast

Purification tag / Conjugate: This CD11b protein is labelled with His tag.

Application: ELISA

Sequence: QLELPVKYAV YLIVTSGEAS TTYLNFTTSE KTIQTMKHQY KFTNLGKRSL PISVVFWVPV RLNNEIVWDR PQVTFSPNLS SACNTEERSP PHSDFLAELE KTHVLNCSIA VCQRIACDIP YFNIQE

Specificity: Cavia porcellus (Guinea pig)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: Integrin alpha-M (ITGAM) (ITGAM Products)

Synonyms: CD11b/CD18 Protein, CR3 Protein, CR3A Protein, Cd11b Protein, F730045J24Rik Protein, Ly-40 Protein, MAC1 Protein, Mac-1 Protein, Mac-1a Protein, CD11B Protein, MAC-1 Protein, MAC1A Protein, MO1A Protein, SLEB6 Protein, C3bi Protein, integrin subunit alpha M Protein, integrin alpha M Protein, integrin, alpha M (complement component 3 receptor 3 subunit) Protein, integrin alpha-M Protein, ITGAM Protein, Itgam Protein, LOC100351865 Protein

Background: Recommended name: Integrin alpha-M.
Alternative name(s): CD11 antigen-like family member B CR-3 alpha chain Cell surface glycoprotein MAC-1 subunit alpha Leukocyte adhesion receptor MO1 CD_antigen= CD11b

UniProt: P11578

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation