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Annexin V Protein (GST tag)

ANXA5 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % (SDS-PAGE) SDS
Catalog No. ABIN1344454
  • Target See all Annexin V (ANXA5) Proteins
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Protein Type
    Recombinant
    Origin
    • 15
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 24
    • 8
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Annexin V protein is labelled with GST tag.
    Application
    SDS-PAGE (SDS)
    Specificity
    Binds to phosphatidylserine (PS).
    Cross-Reactivity
    Human
    Characteristics
    Recombinant human annexin V fused to a GST-tag.
    Purity
    >95 % (SDS-PAGE)
    Top Product
    Discover our top product ANXA5 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstitute with 100 μL sterile water.
    Concentration
    Lot specific
    Buffer
    Lyophilized. In PBS, pH 7.4.
    Storage
    4 °C,-20 °C
    Storage Comment
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C. Reconstituted solutions can be kept at 4°C under sterile conditions for one week or should be frozen in aliquots at -20°C.
    Expiry Date
    12 months
  • Morizono, Chen: "Role of phosphatidylserine receptors in enveloped virus infection." in: Journal of virology, Vol. 88, Issue 8, pp. 4275-90, (2014) (PubMed).

  • Target
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Alternative Name
    Annexin V (ANXA5 Products)
    Background
    Annexin V is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Annexin V competes for phosphatidylserine binding sites (e.g. platelets) with prothrombin or coagulation factors and inhibis the activity of phospholipase A1. Antibodies directed against annexin V are found in patients with a disease called the antiphospholipid syndrome(APS), a thrombophilic disease associated with autoantibodies against phospholipid compounds. Annexin V is used as a probe in the "annexin V affinity assay" to detect cells that have expressed phosphatidylserine on the cell surface, a feature found in apoptosis and other forms of cell death.
    Molecular Weight
    ~52kDa (SDS-PAGE)
    UniProt
    P08758
    Pathways
    Apoptosis
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