Resistin Protein (RETN) (AA 21-114) (DYKDDDDK Tag)
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- Target See all Resistin (RETN) Proteins
- Resistin (RETN)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 21-114
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Origin
- Mouse
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Resistin protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Cross-Reactivity
- Mouse (Murine)
- Characteristics
- Mouse resistin (aa 21-114) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test, Lonza).
- Top Product
- Discover our top product RETN Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.2.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Working aliquots are stable for up to 3 months when stored at -20°C. - Expiry Date
- 3 months
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An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells." in: Cell stem cell, Vol. 9, Issue 1, pp. 74-86, (2011) (PubMed).
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An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells." in: Cell stem cell, Vol. 9, Issue 1, pp. 74-86, (2011) (PubMed).
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- Target
- Resistin (RETN)
- Alternative Name
- Resistin (RETN Products)
- Synonyms
- RETN Protein, ADSF Protein, FIZZ3 Protein, RETN1 Protein, RSTN Protein, XCP1 Protein, Fizz3 Protein, Rstn Protein, Xcp4 Protein, resistin Protein, RETN Protein, Retn Protein
- Background
- The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
- Molecular Weight
- ~15kDa (SDS-PAGE)
- UniProt
- Q99P87
- Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
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