PRKDC Protein (AA 4019-4128) (GST tag)

Catalog No. ABIN1316293

Product Details

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Protein Type: Recombinant

Protein Characteristics: AA 4019-4128

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This PRKDC protein is labelled with GST tag.

Application: Western Blotting (WB), Affinity Purification (AP), Antibody Array (AA), ELISA

Purpose: PRKDC (Human) Recombinant Protein (Q01)

Sequence: KMLKKGGSWI QEINVAEKNW YPRQKICYAK RKLAGANPAV ITCDELLLGH EKAPAFRDYV AVARGSKDHN IRAQEPESGL SEETQVKCLM DQATDPNILG RTWEGREPWM

Characteristics: Human PRKDC partial ORF ( NP_008835, 4019 a.a. - 4128 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Pyun, Seo, Lee, Jin, Kim, Kim, Kim, Nam, Yook, Lee: "Mutual regulation between DNA-PKcs and Snail1 leads to increased genomic instability and aggressive tumor characteristics." in: Cell death & disease, Vol. 4, pp. e517, (2013) (PubMed).

Target Details

Target: PRKDC (Protein Kinase, DNA-Activated, Catalytic Polypeptide (PRKDC))

Alternative Name: PRKDC (PRKDC Products)

Synonyms: DNA-PKcs Protein, DNAPK Protein, DNPK1 Protein, HYRC Protein, HYRC1 Protein, XRCC7 Protein, p350 Protein, DNA-PKCS Protein, dna-pkcs Protein, dnapk Protein, dnpk1 Protein, hyrc Protein, hyrc1 Protein, prkdc-A Protein, xrcc7 Protein, PRKDC Protein, AI326420 Protein, AU019811 Protein, DNAPDcs Protein, DOXNPH Protein, dxnph Protein, p460 Protein, scid Protein, slip Protein, protein kinase, DNA-activated, catalytic polypeptide Protein, protein kinase, DNA-activated, catalytic polypeptide L homeolog Protein, DNA-dependent protein kinase catalytic subunit Protein, protein kinase, DNA activated, catalytic polypeptide Protein, PRKDC Protein, prkdc.L Protein, LOC100633457 Protein, Prkdc Protein

Background: Full Gene Name: protein kinase, DNA-activated, catalytic polypeptide
Synonyms: DNA-PKcs,DNAPK,DNPK1,HYRC,HYRC1,XRCC7,p350

Gene ID: 5591

NCBI Accession: NM_006904

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response