Mre11 Protein (AA 1-206) (GST tag)

Catalog No. ABIN1311266

Product Details

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Protein Type: Recombinant

Protein Characteristics: AA 1-206

Origin: Human

Source: Wheat germ

Purification tag / Conjugate: This Mre11 protein is labelled with GST tag.

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Purpose: MRE11A (Human) Recombinant Protein (P01)

Sequence: MSTADALDDE NTFKILVATD IHLGFMEKDA VRGNDTFVTL DEILRLAQEN EVDFILLGGD LFHENKPSRK TLHTCLELLR KYCMGDRPVQ FEILSDQSVN FGFSKFPWVN YQDGNLNISI PVFSIHGNHD DPTGADALCA LDILSCAGFV NHFGRSMSVE KIDISPVLLQ KGRTKIALYG LGSIPDERLY RMFVNKKVTM LRPKED

Characteristics: Human MRE11A full-length ORF ( AAH05241, 1 a.a. - 206 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Lee, Padget, Curtis, Cowell, Moiani, Sondka, Morris, Jackson, Cockell, Tainer, Austin: "MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA." in: Biology open, Vol. 1, Issue 9, pp. 863-73, (2012) (PubMed).

Target Details

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Alternative Name: MRE11A (MRE11A Products)

Synonyms: wu:faa63d12 Protein, zgc:64018 Protein, Mre11 Protein, Mre11b Protein, ATLD Protein, HNGS1 Protein, MRE11 Protein, MRE11B Protein, MRE11 homolog A, double strand break repair nuclease Protein, MRE11 homolog, double strand break repair nuclease Protein, MRE11A homolog A, double strand break repair nuclease Protein, mre11a Protein, MRE11 Protein, Mre11a Protein

Background: Full Gene Name: MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
Synonyms: ATLD,HNGS1,MRE11,MRE11B

Gene ID: 4361

Pathways: DNA Damage Repair