IL12 Protein
-
- Target See all IL12 Proteins
- IL12 (Interleukin 12 (IL12))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Application
- Biochemical Assay (BCA)
- Sequence
- p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNASp40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLYENY TSSFFIRDII KPDPPKNLQL KPLKNSRQVE VSWEYPDTWS TPHSYFSLTF CVQVQGKSKR EKKDRVFTDK TSATVICRKN ASISVRAQDR YYSSSWSEWA SVPCS.
- No Cross-Reactivity
- Mouse (Murine), Monkey, Bacteria
- Characteristics
- The ED50 was determined by the induction of IFN-gamma from NK cells co-stimulated with IL-18 is less or equal to 1.0 ng/ml, corresponding to a specific activity of greater than or equal to 1 x 10^6 units/mg.
- Purity
- > 95 % as determined by SDS-PAGE analysis.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Endotoxin: 1.EU/µg determined by LAL method.
- Top Product
- Discover our top product IL12 Protein
-
-
- Comment
-
Length: 503 AA
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- We recommended spin the vial shortly prior to opening to bring the contents to the bottom. Lyophilized hIL12 should be reconstituted in deionized water to 0,1-1 µg/mL to regain full activity. These stock solutions should be apportioned into working aliquots and stored at -20 °C. Further dilutions should be made in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA.
- Storage
- -20 °C
-
- Target
- IL12 (Interleukin 12 (IL12))
- Alternative Name
- IL-12 (IL12 Products)
- Molecular Weight
- 75 kDa.
- Pathways
- JAK-STAT Signaling, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
-