Ephrin B3 Protein (EFNB3) (His tag)

Catalog No. ABIN1098662

Product Details

Target: Ephrin B3 (EFNB3)

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This Ephrin B3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purity: > 90 % by SDS - PAGE

Application Details

Comment:

Synonyms: Ephrin-B3, EFL6, EPLG8, LERK8

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 M NaCl, 2 M Urea

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: Ephrin B3 (EFNB3)

Alternative Name: EFNB3 (EFNB3 Products)

Synonyms: efnb3-A Protein, EphB3 Protein, EFNB3 Protein, efnb3 Protein, id:ibd5049 Protein, zgc:111938 Protein, EFL-6 Protein, ELF-3 Protein, Elk-L3 Protein, Epl8 Protein, LERK-8 Protein, NLERK-2 Protein, ELK-L3 Protein, RGD1565678 Protein, EFL6 Protein, EPLG8 Protein, LERK8 Protein, ephrin B3 Protein, ephrin-B3 L homeolog Protein, ephrin-B3b Protein, ephrin-B3 Protein, EFNB3 Protein, efnb3.L Protein, efnb3b Protein, efnb3 Protein, Efnb3 Protein

Background: EFNB3, also known as ephrin-B3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. It binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. Recombinant human EFNB3 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 24.6 kDa (224aa)

NCBI Accession: NP_001397

Pathways: RTK Signaling