Glucose-6-Phosphate Dehydrogenase Protein (G6PD) (His tag)
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- Target See all Glucose-6-Phosphate Dehydrogenase (G6PD) Proteins
- Glucose-6-Phosphate Dehydrogenase (G6PD)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Hi-5 Cells
- Purification tag / Conjugate
- This Glucose-6-Phosphate Dehydrogenase protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by using conventional chromatography.
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product G6PD Protein
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- Comment
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Synonyms: glucose-6-phosphate 1-dehydrogenase, G6PD1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1 MM PMSF, 2 mM EDTA, 2 mM DTT, 200 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- Glucose-6-Phosphate Dehydrogenase (G6PD)
- Alternative Name
- G6PD (G6PD Products)
- Background
- Glucose-6-phosphate dehydrogenase (G6PD) is the rate-limiting enzyme of the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells by maintaining the level of NADPH. G6PD converts glucose-6-phosphate into 6-phosphoglucono-delta-lactone and simultaneously produce NADPH. The NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. G6PD deficiency cause acute hemolytic anemia. Recombinant human G6PD protein, fused to His-tag at N-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.
- Molecular Weight
- 61.4kDa (535aa)
- NCBI Accession
- NP_001035810
- Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
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