OBFC1 Protein (His tag)
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- Target See all OBFC1 Proteins
- OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This OBFC1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product OBFC1 Protein
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- Comment
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Synonyms: CST complex subunit STN1, AAF-44, RPA-32, STN1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 20% glycerol, 1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- OBFC1 (Oligonucleotide/oligosaccharide-Binding Fold Containing 1 (OBFC1))
- Alternative Name
- OBFC1 (OBFC1 Products)
- Synonyms
- AAF-44 Protein, AAF44 Protein, RP11-541N10.2 Protein, RPA-32 Protein, STN1 Protein, bA541N10.2 Protein, 0610009H20Rik Protein, 2310057J23Rik Protein, AI413458 Protein, zgc:64174 Protein, ATSTN1 Protein, F10K1.17 Protein, F10K1_17 Protein, STN1, CST complex subunit Protein, Nucleic acid-binding, OB-fold-like protein Protein, STN1 Protein, Stn1 Protein, stn1 Protein
- Background
- CST complex subunit STN1, also known as OBFC1, is a component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites. Recombinant human OBFC1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 44.5 kDa (391aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_079204
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