PTGR2 Protein (His tag)
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- Target See all PTGR2 Proteins
- PTGR2 (Prostaglandin Reductase 2 (PTGR2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PTGR2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product PTGR2 Protein
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- Comment
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Synonyms: Prostaglandin reductase 2, PGR2, ZADH1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- PTGR2 (Prostaglandin Reductase 2 (PTGR2))
- Alternative Name
- PTGR2 (PTGR2 Products)
- Synonyms
- ZADH1 Protein, MGC146252 Protein, PGR2 Protein, 1810016I24Rik Protein, 9130222H03Rik Protein, 9630002F03Rik Protein, AI838763 Protein, B830026H24Rik Protein, PGR-2 Protein, PRG-2 Protein, Zadh1 Protein, prostaglandin reductase 2 Protein, prostaglandin reductase 2 S homeolog Protein, PTGR2 Protein, ptgr2 Protein, ptgr2.S Protein, Ptgr2 Protein
- Background
- PTGR2 belongs to the medium-chain dehydrogenase/reductase superfamily. PTGR2 catalyzes an NADPH-dependent reduction of the conjugated alpha,beta-unsaturated double bond of 15-keto-PGE(2), a key step in terminal inactivation of prostaglandins and suppression of PPARgamma-mediated adipocyte differentiation. Selective inhibition of PTGR2 may contribute to the improvement of insulin sensitivity with fewer side effects. Recombinant human PTGR2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 41.1 kDa (375aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_689657
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